Nuclear Factor-KappaB (NF-KappaB) is a heterodimeric protein made up of various combinations of Rel family transcription factor members. NF-KappaB is activated via the conventional and noncanonical (or alternative) signaling pathways, which, although having different signaling mechanisms, are both crucial for controlling immunological and inflammatory responses. NF-KappaB plays a crucial role in carcinogenesis and is a key regulator of cell fate choices, including the regulation of proliferation and programmed cell death. Toll-like receptors on innate immune system cells that recognize bacterial and viral products also induce NF-KappaB, which triggers the generation of proinflammatory cytokines and the activation of antigen-presenting cells for T-cell costimulation in the adaptive immunological response. Recent research has emphasized the significance of the link between NF-KappaB, inflammation, and cancer as well as the importance of treatments that control NF-KappaB activity.
Abeomics offers a wide variety of polyclonal and monoclonal antibodies, including TRF2, RANK, p50, RANKL, p65, NFKBIL1, and many more which help scientists and researchers conduct research more effectively.
NF-kB Pathway
77 PRODUCTS FOUND
-
Catalogue No: 12-4344 Clonality: Monoclonal Application: FACS Reactivity: Human Format: Purified 200 μl - $690.00
20 μl - $428.00
-
Catalogue No: 12-4316 Clonality: Monoclonal Application: FACS Reactivity: Human Format: Purified 200 μl - $690.00
20 μl - $428.00
-
Catalogue No: 12-4315 Clonality: Monoclonal Application: WB Reactivity: Human Format: Purified 200 μl - $690.00
20 μl - $428.00
-
Catalogue No: 12-4307 Clonality: Monoclonal Application: FACS, WB Reactivity: Human Format: Purified 200 μl - $690.00
20 μl - $428.00
-
Catalogue No: 12-4139 Clonality: Monoclonal Application: WB Reactivity: Human Format: Purified 200 μl - $690.00
20 μl - $428.00
-
Catalogue No: 35-1634 Clonality: Polyclonal Application: WB, IF Reactivity: Rat, Mouse, Human Format: Purified 50 μl - $374.00
100 μl - $437.00
-
Catalogue No: 35-1630 Clonality: Polyclonal Application: WB, IF Reactivity: Rat, Mouse, Human Format: Purified 50 μl - $374.00
100 μl - $437.00
-
Catalogue No: 35-1625 Clonality: Polyclonal Application: IHC, WB, IF Reactivity: Rat, Mouse, Human Format: Purified 50 μl - $374.00
100 μl - $437.00
-
Catalogue No: 35-1624 Clonality: Polyclonal Application: IHC, WB Reactivity: Rat, Mouse, Human Format: Purified 50 μl - $374.00
100 μl - $437.00
-
Catalogue No: 35-1585 Clonality: Polyclonal Application: IHC, WB Reactivity: Rat, Mouse, Human Format: Purified 50 μl - $374.00
100 μl - $437.00