Anti-BSEP Monoclonal Antibody (Clone:IHC518)
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$394.00
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| Product code: | 44-1006 |
|---|---|
| Clone name : | IHC518 |
| Clonality : | Monoclonal |
| Reactivity : | Human |
|---|
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| Amount | 0.5 ml |
|---|---|
| Isotype | Mouse IgG1 |
| Purification | Protein A/G Chromatography |
| Content | Tris Buffer, pH 7.3 - 7.7, with 1% BSA and |
| Storage condition | Store at 2°C - 8°C. Do not freeze. |
| Alternative Name | ABCB11||BSEP |
| Gene | ABCB11 |
|---|---|
| Gene ID | 8647 |
| Uniprot ID | O95342 |
| Alternative Name | ABCB11||BSEP |
Bile Salt Export Pump (BSEP) is a member of the ATP-binding cassette (ABC) transporters, which mediates the transport of bile acid, taurocholate and other cholate conjugates across the hepatocyte canalicular membrane into the canaliculus. BSEP is associated with progressive familial intrahepatic cholestasis type 2 (PFIC2) and benign recurrent intrahepatic cholestasis type 2 (BRIC2). PFIC2 caused by mutations in the BSEP gene increases the risk of hepatocellular carcinoma in early life
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