Anti-GAPDHS Monoclonal Antibody (Clone:Hs-8)
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$365.00
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| Product code: | 30-1189 |
|---|---|
| Clone name : | Hs-8 |
| Application : | WB |
|---|---|
| Reactivity : | Human |
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| Amount | 0.1 mg |
|---|---|
| Isotype | Mouse IgM |
| Purification | Purified by precipitation and chromatography |
| Storage condition | Store at 2-8°C. Do not freeze. |
| Alternative Name | GAPDHS||GAPD2||GAPDH2||GAPDS||HSD-35||HSD35 |
| Gene | GAPDHS |
|---|---|
| Gene ID | 26330 |
| Uniprot ID | O14556 |
| Alternative Name | GAPDHS||GAPD2||GAPDH2||GAPDS||HSD-35||HSD35 |
GAPDHS (the sperm-specific glyceraldehyde phosphate dehydrogenase, also known as GAPD2, GAPDS, HSD-35, or GAPDH-2, is a glycolytic enzyme that plays an important role in carbohydrate metabolism. Like its somatic cell counterpart, this sperm-specific enzyme functions in a nicotinamide adenine dinucleotide-dependent manner to remove hydrogen and add phosphate to glyceraldehyde 3-phosphate to form 1,3-diphosphoglycerate. During spermiogenesis, this enzyme may play an important role in regulating the switch between different energy-producing pathways, and it is required for sperm motility and male fertility. It can be used as an intra-acrosomal marker for evaluation of the physiological state of sperm cells as well as for selection of a suitable method of fertilization in the laboratories of assisted reproduction.
Application Note:
Western Blotting Immunocytochemistry Recommended dilution: Purified Antibody: 10 µg/ml Staining technique: Membrane permeabilization (acetone) is essential. Flow Cytometry
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