Mouse Monoclonal Antibody to Human PD-1 (Clone : PD1.D3)
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| Product code: | 45-1074 |
|---|---|
| Clone name : | PD1.D3 |
| Application : | ELISA |
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| Isotype | Mouse IgG1,Kappa |
|---|---|
| Purification | Protein A chromatography |
| Content | 0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide. |
| Storage condition | The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles. |
| Alternative Name | Programmed cell death protein 1, Protein PD-1, hPD-1, CD279 |
| Gene ID | 5133 |
|---|---|
| Uniprot ID | Q15116 |
| Alternative Name | Programmed cell death protein 1, Protein PD-1, hPD-1, CD279 |
| Immunogen Information | Recombinant human PD-1-Fc |
Programmed cell death protein 1 (PD-1), is cell surface receptor expressing on T cells and pro-B cells. Binding of its two ligands PD-L1 and PD-L2 could result in down-regulation of the immune system by inhibiting the T-cell activation process. Thus, PD-1 is an important immune checkpoint and popular target for therapeutic antibodies against many cancers. Anti-Human PD-1 Antibody (PD1.D3), mAb, Mouse is produced from the hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from mouse immunized with recombinant human PD-1-Fc .
Application Note:
ELISA detection: 0.01-0.1 μg/ml
ELISA blocking: 10-15 μg/ml
Flow cytometry: 5-10 μg/ml
Blockade of Receptor-ligand Interaction in Flow cytometry: 5 μg/ml
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