Phospho-c-Fos (Ser32) (Clone: BA9) rabbit mAb
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$428.00
In stock
| Product code: | 12-4328 |
|---|---|
| Clone name : | cFosS32-BA9 |
| Clonality : | Monoclonal |
| Application : | FACS |
|---|---|
| Reactivity : | Human |
| Conjugate : | Unconjugated |
Shipping Info:
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| Amount | 200 l μl |
|---|---|
| Isotype | Rabbit IgG1k |
| Content | 1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% BSA |
| Storage condition | Store at -20°C. Avoid repeated freeze and thaw cycles. |
| Alternative Name | Proto-oncogene c-Fos, Cellular oncogene fos, G0/G1 switch regulatory protein 7, G0S7 |
| Alternative Name | Proto-oncogene c-Fos, Cellular oncogene fos, G0/G1 switch regulatory protein 7, G0S7 |
|---|
c-FOS belongs to the Fos family of nuclear oncogenes which include Fos B, Fos-related antigen 1 (FRA1), Fos-related antigen 2 (FRA2) in addition to c-Fos(1). Activator Protein-1 (AP-1) is formed upon dimerization of Fos proteins with Jun protiens (c-Jun, Jun B, and JunD)(2,3). AP-1 is considered a transcription factor that binds to TRE/AP-1 elements and activates transcription. ERK5 is involved with c-Fos phosphorylation at Ser32 and Thr232 which increase c-Fos stability and its nuclear translocation.
Application Note:
1μg/mL - 0.001μg/mL. It is recommended that the reagent be titrated for optimal performance for each application. See product image legends for additional information.(0.5mg/ml, more than 200 western blots)
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