Polyclonal Antibody to DNA PKcs (Ab-2609)
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$374.00
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| Product code: | 35-1521 |
|---|---|
| Clonality : | Polyclonal |
| Application : | WB |
|---|---|
| Reactivity : | Human |
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| Isotype | Rabbit IgG |
|---|---|
| Content | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage condition | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
| Alternative Name | DNPK1|| PRKD|| PRKDC|| XRCC7|| P460 |
| Gene | PRKDC |
|---|---|
| Gene ID | 5591 |
| Uniprot ID | P78527 |
| Alternative Name | DNPK1|| PRKD|| PRKDC|| XRCC7|| P460 |
The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties
Application Note:
Predicted MW: 450kd, Western blotting: 1:500~1:1000
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