Polyclonal Antibody to eIF4B (Ab-422)
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$374.00
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| Product code: | 35-1728 |
|---|---|
| Clonality : | Polyclonal |
| Application : | IHC, WB |
|---|---|
| Reactivity : | Rat, Mouse, Human |
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| Isotype | Rabbit IgG |
|---|---|
| Content | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage condition | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
| Alternative Name | EIF4B |
| Gene | EIF4B |
|---|---|
| Gene ID | 1975 |
| Uniprot ID | P23588 |
| Alternative Name | EIF4B |
Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.
Gingras, A.C. et al. (2001) Genes Dev. 15, 807-826.
Duncan, R. and Hershey, J.W. (1985) J. Biol. Chem. 260, 5493-5497.
Duncan, R.F. and Hershey, J.W. (1989) J. Cell Biol. 109, 1467-1481.
Application Note:
Predicted MW: 80kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
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