Polyclonal Antibody to HIF2A
As low as
$374.00
In stock
| Product code: | 35-1858 |
|---|---|
| Clonality : | Polyclonal |
| Application : | WB |
|---|---|
| Reactivity : | Human |
Shipping Info:
For estimated delivery dates, please contact us at support@abeomics.com
| Isotype | Rabbit IgG |
|---|---|
| Content | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage condition | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
| Alternative Name | HLF|| MOP2|| ECYT4|| HIF2A|| PASD2 |
| Gene | EPAS1 |
|---|---|
| Gene ID | 2034 |
| Uniprot ID | Q99814 |
| Alternative Name | HLF|| MOP2|| ECYT4|| HIF2A|| PASD2 |
Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation seems to require recruitment of transcriptional coactivators such as CREBPB and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD.
Application Note:
Western blotting: 1:500~1:1000
Write Your Own Review