Polyclonal Antibody to Histone H3.1 (Phospho-Ser10)
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$374.00
In stock
| Product code: | 35-1174 |
|---|---|
| Clonality : | Polyclonal |
| Application : | IHC, WB, IF |
|---|---|
| Reactivity : | Rat, Mouse, Human |
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| Isotype | Rabbit IgG |
|---|---|
| Content | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage condition | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
| Alternative Name | H3/b||H3FB |
| Gene | HIST1H3A |
|---|---|
| Gene ID | 8350 |
| Uniprot ID | P68431 |
| Alternative Name | H3/b||H3FB |
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Dai J, et al. (2005) Genes Dev 19(4): 472-488.
Yih LH, et al. (2005) Carcinogenesis 26(1): 53-63.
Application Note:
Predicted MW: 17kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
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